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Human domain antibodies against components of the human insulin-like growth factor (IGF) system
专利权人:
THE UNITED STATES OF AMERICA; as represented by THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
DIMITROV, Dimiter S.,CHEN, Weizao
申请号:
AU2014256364
公开号:
AU2014256364A1
申请日:
2014.10.30
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2014256364A120141120.pdf#####ABSTRACT OF THE DISCLOSURE The invention provides antibodies or antibody fragments that bind to insulin-like growth factor (IGF) 1 receptor (IGF-1R) or IGF-2, as well as method of using the antibodies for inhibiting the IGF-mediated signaling pathway, inhibiting IGF-1R signaling, and treating cancer. The invention also provides a method of detecting the presence of IGF-1R or IGF-2 in a sample using the inventive antibodies and antibody fragments. 5902956_1 (GHMatters) P89761.AU.1 LEOWNR
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