SASIKUMAR, POTTAYIL GOVINDAN NAIR,RAMACHANDRA, MURALIDHARA,RAMACHANDRA, RAGHUVEER KALLAJHARI,LAZORCHAK, ADAM S.,WYANT, TIMOTHY L.
申请号：
CA3081675
公开号：
CA3081675A1
申请日:
2018.10.31
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present disclosure relates to methods comprising administering compounds that inhibit VISTA and PD-1 (e.g., PD-1, PD-L1 or PD-L2) pathways with a compound that inhibits TIM-3 and PD-1 (e.g., PD-1, PD-L1 or PD-L2) pathways.The disclosure also relates to treatment of disorders by inhibiting an immunosuppressive signal induced by VISTA, TIM-3, PD-1, PD-L1, and/or PD-L2.
