SASIKUMAR, Pottayil Govindan Nair,RAMACHANDRA, Muralidhara,RAMACHANDRA, Raghuveer Kallajhari,LAZORCHAK, Adam S.,WYANT, Timothy L.
申请号:
AU2018360389
公开号:
AU2018360389A1
申请日:
2018.10.31
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present disclosure relates to methods comprising administering compounds that inhibit VISTA and PD-1 (e.g., PD-1, PD-L1 or PD-L2) pathways with a compound that inhibits TIM-3 and PD-1 (e.g., PD-1, PD-L1 or PD-L2) pathways.The disclosure also relates to treatment of disorders by inhibiting an immunosuppressive signal induced by VISTA, TIM-3, PD-1, PD-L1, and/or PD-L2.