Pottayil Govindan N. Sasikumar,Muralidhara Ramachandra,Raghuveer K. Ramachandra,Adam S. Lazorchak,Timothy L. Wyant
申请号：
US16761964
公开号：
US20200289477A1
申请日:
2018.10.31
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to methods comprising administering compounds that inhibit VISTA and PD-1 (e.g., PD-1, PD-L1, or PD-L2) pathways with a compound that inhibits TIM-3 and PD-1 (e.g., PD-1, PD-L1, or PD-L2) pathways. The disclosure also relates to treatment of disorders by inhibiting an immunosuppressive signal induced by VISTA, TIM-3, PD-1, PD-L1, and/or PD-L2.
