SHEIKH,AHMAD Y.,席可亚曼德 Y,席可亞曼德 Y,MATTEI,ALESSANDRA,马特伊亚乐珊卓,馬特伊亞樂珊卓,WANG,XIU C.,王秀 C
申请号:
TW107147785
公开号:
TW201936625A
申请日:
2014.04.21
申请国别(地区):
TW
年份:
2019
代理人:
摘要:
The present invention relates generally to the compound:N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.本發明概言之係關於化合物:N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-氰基-2,2,6a,6b,9,9,12a-七甲基-10,14-二側氧基-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-十八氫苉-4a-基)-2,2-二氟丙醯胺, 其多晶形、其製備及使用方法、其醫藥組合物及其套組及製品。