BROOKINGS, DANIEL CHRISTOPHER,BROWN, JULIEN ALISTAIR,JACKSON, VICTORIA ELIZABETH,PORTER, JOHN ROBERT,QUINCEY, JOANNA RACHEL
申请号：
CA2930866
公开号：
CA2930866A1
申请日:
2014.12.08
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
A series of substituted imidazo[l,2-b][l,2,4]triazine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders； neurological and neurodegenerative disorders； pain and nociceptive disorders； cardiovascular disorders； metabolic disorders； ocular disorders； and oncological disorders.
