JACKSON, VICTORIA ELIZABETH,HEER, JAG PAUL,HEINELT, UWE
申请号：
CA2986968
公开号：
CA2986968A1
申请日:
2016.06.07
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
A series of substituted fused tricyclic imidazo pyrazine derivatives and analogues thereof, represented by formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders； neurological and neurodegenerative disorders； pain and nociceptive disorders； cardiovascular disorders； metabolic disorders； ocular disorders； and oncological disorders.
