KONRADI, ANDREI WILLIAM,SINGH, SHWETA,LOWMAN, HENRY BERNARD,DESNOYERS, LUC ROLAND,LIANG, TONY W.
申请号:
CA2913732
公开号:
CA2913732A1
申请日:
2014.06.04
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The invention relates generally to compositions and methods for conjugating antibodies and activatable antibodies, and methods of partially reducing antibodies and/or activatable antibodies prior to conjugation, e.g., thiol-based conjugation, with an agent, e.g., a therapeutic and/or diagnostic agent.