Lowman, Henry Bernard,Desnoyers, Luc Roland,Liang, Tony W.,Konradi, Andrei William,Singh, Shweta
申请号:
AU2014274982
公开号:
AU2014274982A1
申请日:
2014.06.04
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The invention relates generally to compositions and methods for conjugating antibodies and activatable antibodies, and methods of partially reducing antibodies and/or activatable antibodies prior to conjugation, e.g., thiol-based conjugation, with an agent, e.g., a therapeutic and/or diagnostic agent.