Henry Bernard Lowman,Luc Roland Desnoyers,Tony W. Liang,Andrei William Konradi,Shweta Singh
申请号:
US15359100
公开号:
US20170072067A1
申请日:
2016.11.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates generally to compositions and methods for conjugating antibodies and activatable antibodies, and methods of partially reducing antibodies and/or activatable antibodies prior to conjugation, e.g., thiol-based conjugation, with an agent, e.g., a therapeutic and/or diagnostic agent.