KUMAR, SANJEEV,WALDO, JESSE,JAIPURI, FIROZ,MAUTINO, MARIO
申请号：
CA2902174
公开号：
CA2902174A1
申请日:
2014.03.10
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Presently provided are inhibitors of IDO and TDO and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase and tryptophan 2,3 dioxygenase； treating immunosuppression； treating a medical conditions that benefit from the inhibition of tryptophan degradation； enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent； treating tumor-specific immunosuppression associated with cancer； and treating immunosupression associated with an infectious disease.
