COMPOSÉS TRICYCLIQUES UTILISÉS EN TANT QU'INHIBITEURS DE L'IMMUNOSUPPRESSION DONT LA MÉDIATION EST ASSURÉE PAR LA MÉTABOLISATION DU TRYPTOPHANE

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专利权人:

Newlink Genetics Corporation

发明人:

申请号：

EP18152869.6

公开号：

EP3366678A1

申请日:

2014.03.10

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Presently provided are inhibitors of IDO and TDO and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase and tryptophan 2,3 dioxygenase； treating immunosuppression； treating a medical conditions that benefit from the inhibition of tryptophan degradation； enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent； treating tumor-specific immunosuppression associates with cancer； and treating immunosupression associated with an infectious disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/