PROBLEM TO BE SOLVED: To compute the concentration of glucose contained in a corium layer while reducing the influence of noise caused by a layer other than the corium layer.SOLUTION: An irradiation part 104 irradiates the skin with short-time pulse light, and a light receiving part 105 receives light backscattered by the skin. A measured light intensity acquiring part 106 acquires the received light intensity of the light receiving part 105 at the time t. An optical absorption coefficient computing part 109 computes an optical absorption coefficient of the corium layer of the skin based on light intensity acquired by the measured light intensity acquiring part 106, the optical path length of each layer of a skin model at the time t stored by an optical path length distribution storage part 102, and the light intensity of the skin model at the time t stored by a time-resolved waveform storage part 103. A concentration computing part 110 computes the glucose concentration of the corium layer based on the optical absorption coefficient of the corium layer computed by the optical absorption coefficient computing part 109. A plurality of light receiving parts 105 are prepared, and the light receiving parts 105 employed in this case have such irradiation light receiving intervals as to cause backscattering in desired layers.COPYRIGHT: (C)2012,JPO&INPIT【課題】真皮層以外の層によるノイズの影響を軽減して、真皮層に含まれるグルコースの濃度を算出する。【解決手段】照射部104は、皮膚に短時間パルス光を照射し、受光部105は、皮膚によって後方散乱した光を受光し、計測光強度取得部106は、時刻tにおける受光部105の受光強度を取得する。光吸収係数算出部109は、計測光強度取得部106が取得した光強度と、光路長分布記憶部102が記憶する時刻tにおける皮膚モデルの各層の光路長と、時間分解波形記憶部103が記憶する時刻tにおける皮膚モデルの光強度とに基づいて、皮膚の真皮層の光吸収係数を算出し、濃度算出部110は、光吸収係数算出部109が算出した真皮層の光吸収係数に基づいて、真皮層のグルコース濃度を算出する。受光部105は複数用意されており、所望の層で後方散乱が生じるような照射受光間隔を有するものが用いられる。【選択図】図1
