PROBLEM TO BE SOLVED: To provide a concentration determination apparatus, a concentration determination method and a program capable of non-invasively and accurately measuring the concentration of a target component contained in an observation object regardless of its temperature variation.SOLUTION: A blood glucose measurement instrument 1, which is a concentration determination apparatus of this invention, comprises: an irradiation part 5 that irradiates skin with light having a specific wavelength of which absorption coefficient of water contained in a dermal layer constituting the skin has small temperature variation a light scattering medium layer selection part 7 that selects back-scattered light emitted by the dermal layer a light receiving part 8 that receives the back-scattered light emitted from the dermal layer a light intensity acquisition part 9 that determines the light intensity of the back-scattered light an optical absorption coefficient calculation part 12 that calculates an optical absorption coefficient of the dermal layer of the skin irradiated with the light having the specific wavelength and a concentration calculation part 13 that calculates a glucose concentration contained in the dermal layer from the optical absorption coefficient of the dermal layer.COPYRIGHT: (C)2012,JPO&INPIT【課題】温度が変化した場合においても、この観測対象に含まれる目的成分の濃度を、非侵襲的に精度良く測定することが可能な濃度定量装置及び濃度定量方法並びにプログラムを提供する。【解決手段】本発明の濃度定量装置である血糖値測定装置1は、皮膚に、この皮膚を構成する真皮層における水の吸収係数の温度変化が小さい特定波長の光を照射する照射部5と、真皮層により放射される後方散乱光を選択する光散乱媒質層選択部7と、真皮層から放射される後方散乱光を受光する受光部8と、この後方散乱光の光強度を取得する光強度取得部9と、特定波長の光を照射した皮膚の真皮層における光吸収係数を算出する光吸収係数算出部12と、真皮層における光吸収係数から真皮層に含まれるグルコースの濃度を算出する濃度算出部13とを備えている。【選択図】図1
