HUIQUAN HAN,JEONGHOON SUN,KEITH SOO-NYUNG KWAK,LEI-TING TONY TAM,XIAOLAN ZHOU
申请号：
BR112014015003
公开号：
BR112014015003A2
申请日:
2012.12.19
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.
