Kerry E. Benenato,Ellalahewage Sathyajith Kumarasinghe,Mark Cornebise
申请号:
US15476253
公开号:
US20170210697A1
申请日:
2017.03.31
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.