Benenato, Kerry E.,Kumarasinghe, Ellalahewage Sathyajith,Cornebise, Mark
申请号:
AU2016324310
公开号:
AU2016324310A1
申请日:
2016.09.16
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.