Kerry E. BENENATO,Ellalahewage Sathyajith KUMARASINGHE,Mark CORNEBISE
申请号:
US16382423
公开号:
US20190314292A1
申请日:
2019.04.12
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.