Chinese Academy of Sciences;Shanghai Institute of Materia Medica
发明人:
申请号:
EP16867946.2
公开号:
EP3381919A1
申请日:
2016.11.22
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention relates to a class of substituted triazolopiperazine compounds represented by formula (I), tautomers, enantiomers, diastereomers, racemates, metabolites, metabolic precursors, and pharmaceutically acceptable salts, esters, prodrugs or hydrate thereof, a preparation methods therefor, intermediates and a use thereof in the preparation of drugs for prevention and treatment of diseases associated with PARP including various ischemic diseases, neurodegenerative diseases and cancers.