Ao Zhang,Zehong Miao,Pingyuan Wang,Shanshan Song,Zilan Song,Xiajuan Huan,Zhoulong Fan,Jian Ding
申请号:
US15987458
公开号:
US20180265516A1
申请日:
2018.05.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a class of substituted triazolopiperazine compounds, tautomers, enantiomers, diastereomers, racemates, metabolites, metabolic precursors, and pharmaceutically acceptable salts, esters, prodrugs or hydrate thereof, a preparation methods therefor, intermediates and a use thereof in the preparation of drugs for prevention and treatment of diseases associated with PARP including various ischemic diseases, neurodegenerative diseases and cancers.