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Ophthalmic compositions with omega-3 fatty acids
专利权人:
Bausch & Lomb Incorporated
发明人:
Coffey, Martin J.
申请号:
AU2012388711
公开号:
AU2012388711B2
申请日:
2012.11.13
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
A suspension comprising a mixture of oniega-3 fatty acids suspended in a formulation vehicle. The formulation vehicle comprises a lightly cross-linked carboxy-containing polymer and a concentration of ionic salt components to provide the suspension with a calculated ionic strength of less than 0.1. The suspension has the following rheological properties, G' >; G" and a suspension yield value of greater than 1 Pa. Also, upon addition of 30 mL of the suspension to a volume of 6 mL to 12 mL of simulated tear fluid, the resulting tear mixture transitions to a liquid form wherein, G" >; G' and the tear mixture has a yield value of less than 0.1 Pa.
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