Michels, Martin,Follmann, Markus,Vakalopoulos, Alexandros,Zimmermann, Katja,Teusch, Nicole,Lobell, Mario,Bierer, Donald,Engel, Karen,Kissel, Maria
申请号:
AU2010305550
公开号:
AU2010305550A1
申请日:
2010.10.01
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates to novel fluoro-substituted 3,5-dicyano-4-(1-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders.