MICHELS MARTIN,FOLLMANN MARKUS,VAKALOPOULOS ALEXANDROS,ZIMMERMANN KATJA,TEUSCH NICOLE,LOBELL MARIO,BIERER DONALD,ENGEL KAREN,KISSEL MARIA
申请号:
ZA201201524
公开号:
ZA201201524B
申请日:
2012.02.29
申请国别(地区):
ZA
年份:
2013
代理人:
摘要:
The present invention relates to novel fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders.