MICHELS, MARTIN,FOLLMANN, MARKUS,VAKALOPOULOS, ALEXANDROS,ZIMMERMANN, KATJA,TEUSCH, NICOLE,LOBELL, MARIO,BIERER, DONALD,ENGEL, KAREN,KISSEL, MARIA
申请号:
SG2012015400
公开号:
SG178990A1
申请日:
2010.10.01
申请国别(地区):
SG
年份:
2012
代理人:
摘要:
The present invention relates to novel fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders.