CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)
发明人:
申请号：
IL19333308
公开号：
IL193333A
申请日:
2008.08.07
申请国别(地区):
IL
年份:
2012
代理人:
摘要：
A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated protein in a plant is also provided. The method to synthesize sialic acid comprises providing a plant comprising a nucleotide sequence encoding N-acetyl neuraminic acid (Neu5Ac) synthase or Neu5Ac lyase, and expressing the nucleotide sequence thereby synthesizing sialic acid. The plant may also co-express a nucleotide sequence encoding one or more than one of an epimerase, a CMP-Neu5Ac synthase, a CMP-Neu5Ac transporter and a sialyltransferase.
