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Crosslinking polypeptide comprising a single chain tetrameric antibody which binds an MHC-MAGE complex that induces apoptosis
专利权人:
Apo-T B.V.
发明人:
WILLEMSEN, Ralph Alexander
申请号:
DK11820899
公开号:
DK2658873T3
申请日:
2011.12.22
申请国别(地区):
DK
年份:
2019
代理人:
摘要:
The present invention relates to a polypeptide comprising at least four domains specifically binding to a certain MHC peptide complex, said domains separated by linker amino acid sequences, thereby providing each domain with the capability to bind a separate MHC peptide complex, to a nucleic acid encoding for such a polypeptide, to a vector comprising such a nucleic acid, to a host cell for expression of such a polypeptide, to a pharmaceutical composition comprising such a polypeptide, and to a kit of parts comprising at least two polypeptides according to the invention.
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