Cross-linked polypeptides that induce apoptosis

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专利权人:

ウィレムセン， ラルフ アレクサンダー;エーピーオー‐ティー;エーピーオー‐ティー ビー．ヴイ．;ビー.ヴイ.

发明人:

ウィレムセン， ラルフ アレクサンダー,ウィレムセン, ラルフ アレクサンダー

申请号：

JP2013547377

公开号：

JP6177137B2

申请日:

2011.12.22

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The present invention relates to a polypeptide comprising at least four domains specifically binding to a certain MHC peptide complex, said domains separated by linker amino acid sequences, thereby providing each domain with the capability to bind a separate MHC peptide complex, to a nucleic acid encoding for such a polypeptide, to a vector comprising such a nucleic acid, to a host cell for expression of such a polypeptide, to a pharmaceutical composition comprising such a polypeptide, and to a kit of parts comprising at least two polypeptides according to the invention.

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http://www.ckcest.cn/home/