A cell implant matrix has a connective porosity of more than 80 % and consists mainly of a mixture of bioresorbable polymers, wherein the matrix has disk-shape and wherein a surface layer on one side of the disk has less than 20 % of the average pore density of the other sides.The matrix is manufactured by providing a bioresorbable polymer layer stratifying, onto the polymer layer, a mixture of a water-soluble solid, at least two polymers differing with respect to their resorption rates, and a solvent for one of the polymers evaporating the solvent optionally followed by compacting the mixture and watering the compacted body to remove the salt.一種細胞植入用之基質,該基質具有大於80%之連接孔隙度並主要由可生物吸收之複數聚合物的混合物所構成,其中該基質為碟形且其中該碟之一側上之表面層的平均孔隙密度小於其他側之平均孔隙密度的20%。該基質係由下列方法所製造:提供可生物吸收之聚合物層;在該聚合物層上單側地使一水溶性固體、具有不同再吸收速率之至少兩種聚合物、及此等聚合物中之一者用之溶劑的一混合物形成膜層;蒸發該溶劑並選擇性地接著壓實該混合物;及對該結實體澆水以移除該鹽。S1‧‧‧製造無孔隙或較少孔隙之聚合物層S3‧‧‧形成兩種聚合物、固體孔隙形成劑、聚合物用之溶劑的一混合物層S5‧‧‧蒸發溶劑S7‧‧‧澆水以移除孔隙形成劑
