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外用組成物
专利权人:
LTD.;TAISHO PHARMACEUTICAL CO.
发明人:
SUZUKI, KAZUHIRO,铃木一裕,鈴木一裕,ARIIZUMI, HIDEHIKO,有泉秀彦,ONO, AI,小野亜衣,NISHIOKU, YOSHINORI,西奥义宪,西奥義憲
申请号:
TW103113403
公开号:
TW201532632A
申请日:
2014.04.11
申请国别(地区):
TW
年份:
2015
代理人:
摘要:
A minoxidil-containing composition for external use, said composition being stable, exhibiting a good feel of use and causing little irritation, that is a cream preparation characterized by comprising minoxidil, 1.5 parts by mass or more, per part by mass of minoxidil, of a higher fatty acid and/or a salt thereof, a thickener and a surfactant and being substantially free from lower alcohols, wherein minoxidil can be dissolved without employing a lower alcohol in such a large amount as usually required for dissolving minoxidil. Examples of the higher fatty acid and/or a salt thereof usable therein include isostearic acid and oleic acid. As an example of the thickener, a carboxyvinyl polymer can be cited. As an example of the surfactant, a nonionic surfactant can be cited. Further, the cream preparation may contain a polyhydric alcohol such as 1,3-butylene glycol, dipropylene glycol, glycerol or propylene glycol. The pH value of the cream preparation is preferably 5-8.本發明係提供一種乳霜劑,其特徵為含有敏諾西代(minoxidil)、相對於1質量份之敏諾西代為1.5質量份以上之高級脂肪酸以及/或其鹽、增黏劑以及界面活性劑,且實質上未含有低級醇,該乳霜劑係無需摻混一般為使敏諾西代溶解所必須的大量的低級醇,即可溶解敏諾西代,安定並具有良好的使用感,且係含有低刺激性之敏諾西代之外用組成物。可使用之高級脂肪酸以及/或其鹽可舉出異硬酯酸、油酸,增黏劑可舉出羧基乙烯聚合物,界面活性劑可舉出非離子性界面活性劑。進而亦可摻混如1,3-丁二醇、二丙二醇、甘油、丙二醇之多元醇。乳霜劑之pH較佳係5~8。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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