Molecules in the Tryptophan-5-Hydroxytryptophan-Serotonin-NAS-Melatonin/6-Hydroxymelatonin Sulfate-Melatonin Receptor 1A pathway in Neurological Diseases
Methods that include determining levels of melatonin pathway agents (melatonin, L-tryptophan, 5-hydroxytryptophan (5-HTP), serotonin, N-acetylserotonin (NAS), and melatonin receptor 1A (MT1)) in Hypoxic-ischemic brain injury in both newborns (HIE) and adults (stroke), and in ALS, and optionally administering these agents to treat these conditions.