Institute of Materia Medica, Chinese Academy of Medical Sciences
发明人:
Zhehui ZHAO,Pingsheng LEI,Lianqiu WU,Shuang YANG,Wenjie WANG,Haijing ZHANG,Xiang LI
申请号：
US17436675
公开号：
US20220143074A1
申请日:
2020.03.05
申请国别(地区):
US
年份:
2022
代理人:
摘要：
The present invention relates to the technical field of medicine, in particular to a chondroitin sulfate polysaccharide, and a semi-synthetic preparation method therefor and the use thereof. A metal salt of the chondroitin sulfate polysaccharide provided by the present invention has an anti-inflammatory effect, and can be used for preparing a drug against inflammatory diseases. In particular, the metal salt of the chondroitin sulfate polysaccharide provided by the present invention has anti-inflammatory and bone-protecting effects, and can be used for preparing a drug against rheumatoid arthritis and for preparing a drug against osteoarthritis. The present invention provides a method for preparing the metal salt of the chondroitin sulfate polysaccharide, and the metal salt of the chondroitin sulfate polysaccharide with different degrees of sulfation can be obtained by semi-synthetic means in the present invention. The method is simple to operate and suitable for large-scale production.
