<;P>;PROBLEM TO BE SOLVED: To provide a new anti-microbially active peptide exhibiting strong anti-microbial activity against microorganisms including gram-positive and gram-negative pathogenic bacteria, and entirely different from the well-known anti-microbial peptide. <;P>;SOLUTION: The anti-microbially active peptide is obtained by modifying an amino acid sequence of a precursor region peptide of an anti-microbial peptide precursor, and exhibits the anti-microbial activity. In the anti-microbially active peptide, the carboxy group present in the side chain of an acidic amino acid residue contained in the precursor region peptide is converted into an amide group. <;P>;COPYRIGHT: (C)2009,JPO&INPIT