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Rab27A inactivating agent
专利权人:
独立行政法人理化学研究所
发明人:
福田 光則,伊藤 敬
申请号:
JP2005333732
公开号:
JP4869685B2
申请日:
2005.11.18
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
<;P>;PROBLEM TO BE SOLVED: To provide a control factor of Rab27A which engages in the transport of a melanosome. <;P>;SOLUTION: This Rab27A deactivator contains either one of the following (a)-(d): (a) a protein consisting of an amino acid sequence expressed with sequence number 2, or a protein consisting of an amino acid sequence deleted, permuted, or added with one or a few amino acids in a protein consisting of an amino acid sequence expressed with sequence number 2, and having Rab27A GTP-ase activity promoting action; (b) a protein consisting of an amino acid sequence expressed with sequence number 4, or a protein consisting of an amino acid sequence deleted, permuted, or added with one or a few amino acids in a protein consisting of an amino acid sequence expressed with sequence number 4, and having Rab27A GTP-ase activity promoting action; (c) a gene coding the (a) or (b) protein; and (d) a recombinant vector containing the gene coding the above (a) or (b) protein. <;P>;COPYRIGHT: (C)2007,JPO&INPIT
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