FORMULATIONS STABLES D'AGENT DE LIAISON A IGG4

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专利权人:

SANOFI

发明人:

SCHNIEDERS, JULIA,USENER, DIRK,YOUSSEF, AHMED,HAGENDORF, ANNIKA,KIRSCH, MARTINA,RUGGEBERG, SABRINA

申请号：

CA2868401

公开号：

CA2868401A1

申请日:

2013.03.26

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

The present invention provides stable pharmaceutical antibody formulations, including liquid drug product formulations and lyophilized drug product formulations, comprising an IgG4 binding agent and a citrate buffer, wherein the pH of the formulation is at or below both pH 6 and the pi of the binding agent. The formulations can be used in the treatment of chronic bowel diseases or rheumatoid arthritis.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/