Julia Schnieders,Dirk Usener,Sabrina Ruggeberg,Ahmed Youssef,Martina Kirsch,Annika Hagendorf
申请号：
US15416289
公开号：
US20170232104A1
申请日:
2017.01.26
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides stable pharmaceutical antibody formulations, including liquid drug product formulations and lyophilized drug product formulations, comprising an IgG4 binding agent and a citrate buffer, wherein the pH of the formulation is at or below both pH 6 and the pI of the binding agent. The formulations can be used in the treatment of chronic bowel diseases or rheumatoid arthritis.
