Julia SCHNIEDERS,Dirk USENER,Sabrina RUGGEBERG,Ahmed YOUSSEF,Martina KIRSCH,Annika Hagendorf
申请号：
US13850849
公开号：
US20140286933A9
申请日:
2013.03.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides stable pharmaceutical antibody formulations, including liquid drug product formulations and lyophilized drug product formulations, comprising an IgG4 binding agent and a citrate buffer, wherein the pH of the formulation is at or below both pH 6 and the pI of the binding agent. The formulations can be used in the treatment of chronic bowel diseases or rheumatoid arthritis.
