Human application of engineered chimeric antigen receptor (CAR) T-cells

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专利权人:

The University of Texas System;Board of Regents

发明人:

Cooper, Laurence J.N.,Torikai, Horoki,Zhang, Ling,Huls, Helen,Wang-Johanning, Feng,Hurton, Lenka,Olivares, Simon,Krishnamurthy, Janani

申请号：

AU2014265487

公开号：

AU2014265487A1

申请日:

2014.05.14

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The present invention concerns methods and compositions for immunotherapy employing a modified T cell comprising a chimeric antigen receptor (CAR). In particular aspects, CAR-expressing T-cells are producing using electroporation in conjunction with a transposon-based integration system to produce a population of CAR-expressing cells that require minimal ex vivo expansion or that can be directly administered to patients for disease (

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/