工程化嵌合抗原受體(CAR)T細胞的人應用

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专利权人:

Board of Regents The University of Texas System

发明人:

COOPER, Laurence, J.N.,WANG-JOHANNING, Feng,TORIKAI, Horoki,HULS, Helen,HURTON, Lenka,KRISHNAMURTHY, Janani,OLIVARES, Simon,ZHANG, Ling

申请号：

HK16110667.3

公开号：

HK1222674A

申请日:

2016.09.08

申请国别(地区):

HK

年份:

2017

代理人:

摘要：

The present invention concerns methods and compositions for immunotherapy employing a modified T cell comprising a chimeric antigen receptor (CAR). In particular aspects, CAR-expressing T-cells are producing using electroporation in conjunction with a transposon-based integration system to produce a population of CAR-expressing cells that require minimal ex vivo expansion or that can be directly administered to patients for disease (e.g., cancer) treatment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/