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HUMAN APPLICATION OF ENGINEERED CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELLS
专利权人:
THE UNIVERSITY OF TEXAS SYSTEM;BOARD OF REGENTS
发明人:
Laurence JN COOPER,Hiroki TORIKAI,Ling ZHANG,Helen HULS,Feng WANG-JOHANNING,Lenka HURTON,Simon OLIVARES,Janani KRISHNAMURTHY
申请号:
US15434595
公开号:
US20170224798A1
申请日:
2017.02.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention concerns methods and compositions for immunotherapy employing a modified T cell comprising a chimeric antigen receptor (CAR). In particular aspects, CAR-expressing T-cells are producing using electroporation in conjunction with a transposon-based integration system to produce a population of CAR-expressing cells that require minimal ex vivo expansion or that can be directly administered to patients for disease (e.g., cancer) treatment.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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