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N5- (2-ethoxyethyl) -N3- (2-pyridinyl) -3,5-piperidindicarboxamide derivatives for use as renin inhibitors
专利权人:
NOVARTIS AG
发明人:
YOKOKAWA, FUMIAKI,EHARA, TAKERU,KAWAKAMI, SHIMPEI,IRIE, OSAMU,SUZUKI, MASAKI,HITOMI, YUKO,TOYAO, ATSUSHI
申请号:
ES08761309
公开号:
ES2541107T3
申请日:
2008.06.23
申请国别(地区):
ES
年份:
2015
代理人:
摘要:
Compound having a structure according to formula III ** Formula ** in which R1 is C1-7 alkyl, which is optionally substituted with one, two or three substituents selected from the group consisting of hydroxyl, halo and C1-C7 alkoxy; R2 is hydrogen, C1-7 alkyl, C1-C7 alkoxy, halo- C1-7 alkyl, halo-C1-C7 alkoxy or C1-C7 alkoxy-C1-C7 alkoxy; R3 is C1-7 alkyl or C3-8 cycloalkyl; and R5 is C1-7 alkyl or C3-8 cycloalkyl; or a salt thereof.Compuesto que tiene una estructura según la fórmula III**Fórmula** en la que R1 es alquilo C1-7, que está sustituido opcionalmente con uno, dos o tres sustituyentes seleccionados del grupo que consiste en hidroxilo, halo y alcoxilo C1-C7; R2 es hidrógeno, alquilo C1-7, alcoxilo C1-C7, halo-alquilo C1-7, halo-alcoxilo C1-C7 o alcoxi C1-C7-alcoxilo C1-C7; R3 es alquilo C1-7 o cicloalquilo C3-8; y R5 es alquilo C1-7 o cicloalquilo C3-8; o una sal del mismo.
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