您的位置: 首页 > 农业专利 > 详情页

COMPOUNDS AND METHODS FOR MODULATING ACTIVITY OF CALCIUM RELEASE CHANNELS
专利权人:
发明人:
JONATHAN ABRAMSON,ROBERT STRONGIN
申请号:
IN8561/DELNP/2011
公开号:
IN2011DN08561A
申请日:
2011.11.03
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
A method for treating or reducing the risk of a ryanodine receptor (RyR) associated condition, disorder, or disease in a mammal, the method comprising administering to the mammal a therapeutically effective amount of a compound having the formula: wherein: R1, R1, R2, R2, R3, and R3 independently are selected from H and an electron-donating group, or alternatively, when R3 and R3 are bonded to two adjacent carbon atoms, R3 and R3, together with the two adjacent carbon atoms, form a 5-membered monocyclic moiety which is fused to the phenyl group and comprises 1-2 heteroatoms selected from O, S, and N provided that: when each of R1, R2, R2, R3 and R3 is H, R1 is not -OCH3 when R1 is -OCH3, at least one of R1, R2, R2, R3 and R3 is not H when R1 is -OCH3 and R3 and R3 are both NH2, at least one of R1, R2, and R^ is not H when R1 is -OCH3 and R3 and R3 are H and NH2, at least one of R1, R2, R2, R3 and R3 is not H and when R1 is OH, at least one of R1, R2, R2, R3 and R3 is not H or a pharmaceutically acceptable salt, hydrate, ester, or prodrug thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充