FINLAY, MAURICE RAYMOND VERSCHOYLE,PERKINS, DAVID ROBERT,NISSINK, JOHANNES WILHELMUS MARIA,RAUBO, PIOTR ANTONI,SMITH, PETER DUNCAN,BAILEY, ANDREW
申请号：
CA3005517
公开号：
CA3005517A1
申请日:
2016.11.30
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
A compound of Formula (I) or a pharmaceutically acceptable salt thereof, is described. Q can be pyridazin-3-yl, 6- fluoropyridazin-3-yl； R1 can be H； R2 and R3 can each independently be C1-C6 alkyl, or R2 and R3 taken together are -(CH2)3； or R1 and R2 taken together can be -(CH2)2- and R3 can be -CH3； R4 halo, -CH3, -OCH3, -OCHF2, -OCF3, or -CN； and n can be 0, 1, or 2. The compound of formula (I) can inhibit glutaminase, e.g., GLS1.
