FINLAY, Maurice,PERKINS, David,NISSINK, Johannes,RAUBO, Piotr,SMITH, Peter,BAILEY, Andrew
申请号：
SG11201803808V
公开号：
SG11201803808VA
申请日:
2016.11.30
申请国别(地区):
SG
年份:
2018
代理人:
摘要：
A compound of Formula (I) or a pharmaceutically acceptable salt thereof, is described. Q can be pyridazin-3-yl, 6- fluoropyridazin-3-yl； R1 can be H； R2 and R3 can each independently be C1-C6 alkyl, or R2 and R3 taken together are -(CH2)3； or R1 and R2 taken together can be -(CH2)2- and R3 can be -CH3； R4 halo, -CH3, -OCH3, -OCHF2, -OCF3, or -CN； and n can be 0, 1, or 2. The compound of formula (I) can inhibit glutaminase, e.g., GLS1.
