ACETYLENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES

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专利权人:

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

发明人:

KUNG, HANK, F,KUNG, MEI, PING

申请号：

NZ57745807

公开号：

NZ577458A

申请日:

2007.12.07

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is a phenyl or pyridine acetylene compound of formula (I) where the substituents are as disclosed in the description. The compound must contain a halogen or halogen isotope. Also disclosed is a composition comprising a compound of formula (I) a diagnostic composition for imaging amyloid deposits comprising a radio labelled compound of formula (I) and the use of a compound of formula (I) for manufacturing a diagnostic composition. Amyloid detection is often used as a diagnosis for Alzheimers disease.

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