Yong-Dae Park,Jung-Joon Min,Seung-Dae Yang,Min-Goo Hur,Seung-Jin Jung,Yeong-Jin Hong,Seung-Hwan Park
申请号：
US16337184
公开号：
US20190224344A1
申请日:
2016.09.29
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a curcumin derivative, a method for producing same, and a photo-acoustic imaging agent comprising the curcumin derivative for detecting beta-amyloid plaque. The curcumin derivative, expressed by chemical formula 1, according to the present invention exhibits superb selective bonding with beta-amyloid, thereby allowing beta-amyloid to be detected by means of an optical or photo-acoustic imaging methods, and, particularly, the curcumin derivative can highly effectively detect photo-acoustic signals with almost no noise by reacting to irradiation of light having a particular wavelength range, and thus can be useful as a composition for detecting beta-amyloid and for diagnosing diseases caused by excessive production of beta-amyloid.
