A pharmaceutical and cosmetic composition comprises at least two of phospholipid complex of flavanolignanes extracted from Silybum marianum, phospholipid complexes of standardized extract of Vitis vinifera or phospholipid complexes of triterpenes extracted from Glycyrrhiza glabra in combination with conventional sun filters and excipients. A pharmaceutical and cosmetic composition comprises at least two of phospholipid complex of flavanolignanes extracted from Silybum marianum (0.1 - 5, preferably 0.5)%, phospholipid complexes of standardized extract of Vitis vinifera (0.1 - 5, preferably 1.5)% or phospholipid complexes of triterpenes extracted from Glycyrrhiza glabra (0.1 - 5, preferably 1.5)% in combination with conventional sun filters and excipients. ACTIVITY : Dermatological; Antiinflammatory. MECHANISM OF ACTION : Conversion of cortisol inhibitor.