The present invention provides a hemostatic porous composite sponge comprisingi) a matrix of a biomaterial andii) one hydrophilic polymeric component comprising reactive groupswherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that- said polymeric component is coated onto a surface of said matrix of a biomaterial, or- said matrix is impregnated with said polymeric material, or- both.本發明提供一種多孔複合止血棉，其包含：i)生物材料基質；及ii)一種包含活性基團之親水性聚合組分；其中i)與ii)係彼此締合以保留聚合組分之活性，其中締合意謂：- 該聚合組分塗佈於該生物材料基質之表面上；或- 該基質經該聚合材料浸漬；或- 二者。
