KWAN, MIN-FUN, RUDOLF,KRAMER, E., DOUGLAS,FETTERLY, GERALK, J.,HUNG, CHEUNG-TAK,JACKSON, CHRISTOPHER GLYN CHARLES, ALEXANDER,GLUE, PAUL, WILLIAM
申请号:
CA2993127
公开号:
CA2993127A1
申请日:
2016.07.21
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The application pertains to pharmaceutical combinations of orally administered paclitaxel and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity -type infusion reactions, and other negative outcomes resulting from or associated with intravenously administered paclitaxel (e.g., Taxol® or paclitaxel formulated with Cremophor®) therapy in a subject suffering from cancer.