Min-Fun Rudolf KWAN,E. Douglas KRAMER,Gerald J. FETTERLY, Jr.,Cheung-Tak HUNG,Christopher Glyn Charles Alexander JACKSON,Paul William GLUE
申请号:
US15745490
公开号:
US20180207148A1
申请日:
2016.07.21
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The application pertains to pharmaceutical combinations of orally administered paclitaxel and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity-type infusion reactions, and other negative outcomes resulting from or associated with intravenously administered paclitaxel (e.g., Taxol® or paclitaxel formulated with Cremophor®) therapy in a subject suffering from cancer.