Min-Fun Rudolf KWAN,E. Douglas KRAMER,David Lawrence CUTLER,Johnson Yiu-Nam LAU,Wing Kai CHAN
申请号：
US16715753
公开号：
US20200188363A1
申请日:
2019.12.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure provides pharmaceutical combinations of orally administered irinotecan and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity-type infusion reactions, and other negative outcomes resulting from or associated with intravenously administered irinotecan (e.g., Camptosar®) therapy in a subject suffering from cancer.
